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Its molecular formula is C22H34N6O16S4. It is a mixed form of diastereoisomers and ademetionine ions. It is also called a short form SAM-e. It is naturally synthesized in tissues and body fluids and plays an essential role in many biological functions. It works with vitamin B12 and folate. SAM-e is good for the liver, immune system, and nervous system.
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S-Adenosyl-L-Methionine Disulfate P-Toluene-Sulfonate is the disulfate salt of the stable p-toluene-sulfonate complex of s-adenosyl-L-methionine (SAMe).
Items | Specification | Test Methods |
---|---|---|
Physical Analysis | ||
Description | Powder | Organoleptic |
Color | White to off-white | Organoleptic |
Odor | Characteristic | Organoleptic |
Taste | Characteristic | Organoleptic |
Loss on drying | NMT 3.0% w/w | USP<731> |
Identification: Infrared | Complies to Reference Spectrum | IR |
Identification: HPLC | The retention time of a major peak meets the reference sample | HPLC |
Sulphated Ash | NMT 0.5% | USP |
S,S-Isomer | NLT 75.0% | HPLC |
SAM-e ION | 49.5 - 54.7% | HPLC |
P-Toluenesulfonic Acid | 21.0% - 24.0% | USP |
Content of Sulfate (SO4) | 23.5% - 26.5% | HPLC |
S-Adenosyl-L-methionine Disulfate Tosylate | 95.0% - 103% | HPLC |
S-Adenosyl-L-Homocysteine | NMT 1% | HPLC |
Adenine | NMT 1% | HPLC |
Methylthioadenosine | NMT 1.5% | HPLC |
Adenosine | NMT 1% | HPLC |
Total Impurities | NMT 3.5% | HPLC |
pH (5% Aqueous Solution) | 1.0 - 2.0 | USP |
Total Heavy Metals | NMT 10 ppm | USP<231> |
Lead | NMT 1 ppm | USP<232> |
Arsenic | NMT 1 ppm | USP<232> |
Mercury | NMT 0.5 ppm | USP<232> |
Cadmium | NMT 0.5 ppm | USP<232> |
Microbiology Test | ||
Total Plate Count | NMT 10,000 cfu/g | USP<61> |
Yeast & Mold | NMT 100 cfu/g | USP<61> |
E. Coli | Negative/10 g | USP<62> |
Salmonella | Negative/10 g | USP<62> |
Staphylococcus aureus | Negative/10 g | USP<62> |
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