Botanical Name: Pausinystalia johimbe
Plant Part Used: Bark
Processing Method: Extraction
Pausinystalia johimbe is commonly called Yohimbe that belongs to the family Rubiaceae. It is resident in Western and Central Africa. Mainly the bark of the tree is used for many herbal medicines. The major active component of Yohimbe is yohimbine. Yohimbine is an indole alkaloid. Yohimbine is also known as quebrachine. It is a dietary supplement, rich in antioxidants. It has many medicinal values.
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We can determine Yohimbine content by using different analytical methods. HPLC method is the most used and accurate one. The method used here is HPLC.
|Mesh size||95% Passes through #80 mesh||USP<786>|
|Loss on drying||NMT 10.0% w/w||USP<731>|
|Total Alkaloids||NLT 30%||Spectrophotometer|
|Tapped Bulk Density||NLT 0.5 gm/ml||USP<616>|
|Residual Solvent - Methanol||NMT 3000 ppm||GC|
|Assay- Yohimbine (On dry basis)||NLT 8.00%||HPLC|
|Residual-Solvent - Chloroform||NMT 60 ppm||GC|
|Identification||Correspond to standard||USP|
|Total Heavy Metals||NMT 10 ppm||USP<231>|
|Lead||NMT 3 ppm||USP<232>|
|Arsenic||NMT 1 ppm||USP<232>|
|Mercury||NMT 0.5 ppm||USP<232>|
|Cadmium||NMT 0.5 ppm||USP<232>|
|Total Plate Count||NMT 10,000 cfu/g||USP<61>|
|Yeast & Mold||NMT 1000 cfu/g||USP<61>|